A unique Na/H antiport system and spore development in Bacillus subtilis
نویسندگان
چکیده
The function of a principal Na+/H+ antiporter, ShaA, of Bacillus subtilis, is required for the progression of the sporulation process. The step(s) in the sporulation process that requires the function of ShaA was determined. The period of time when the shaA-disrupted B. subtilis showed Na+ sensitivity during its sporulation was confined to the initial stage of sporulation. It was revealed that shaA mutation affects the two key regulatory proteins, σH and Spo0A∼P, that govern the global changes in the gene expression when cells undergo sporulation. S. Kosono
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